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The humoral response in cattle treated with ERA strain rabies vaccine, was studied utilizing the following criteria: antibody titres determined by RFFIT, seroimmunological monitoring of experimentally vaccinated animals, a comparison of data obtained from cattle vaccinated and maintained under field conditions in the absence of anamnestic information. The average antibody responses in the field experiment are in agreement with the laboratory animal response, both showing highest levels at day 15 after vaccination; at day 30 in both groups the immune response is sensibly lower, to remain then on a constant level after day 90 and stay about 0.5 I.U./ml up to the fifteenth month.
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