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After injection of acetyl-[103Ru]-ruthenocene, high 103Ru concentration are found in adrenals of female mice. This was also found with acetyl-[3H]ruthenocene. On autoradiography only the adrenal cortex, not the medulla, was labelled. High 103Ru accumulations did not occur in the adrenals of male mice or rats, but male rats exhibited a very high 103Ru concentration in the kidney, with concentration kidney/muscle ratios up to 780:1. The 103Ru-concentration in the kidney of female rats was only 1/20 that of male rats. After application of testosterone propionate to female mice or estradiol to male rats a drastic change in organ distribution was observed: the 103Ru radioactivity in adrenals and kidneys decreased by a factor of 15. Similar to these results obtained with acetylruthenocen, a sex-specific distribution, but to a lesser extent, was found with dihydroacetylruthenocens.
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
January 1963,
Medical journal of Osaka University,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
January 1979,
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
December 1970,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
March 1958,
Journal de physiologie,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
February 1995,
Appetite,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
March 1947,
Proceedings of the Royal Society of London. Series B, Biological sciences,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
January 1986,
Drug metabolism and disposition: the biological fate of chemicals,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
January 1964,
Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
September 1987,
Clinical pharmacy,
M Wenzel, and
G Schachschneider, and
M Schneider, and
R Herken
April 1949,
Endocrinology,
