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Investigations Jensen's sarcoma-bearing Wistar rats demonstrate the possibility to increase significantly the oncolytic effect of an apathogenic strain of Clostridium butyricum (5 x 10(8) spores of Cl. oncolyticum M 55 i.v.) by an artificial short time hyperglycaemia (achieved maximum blood level of glucose 28.87 +/- 8.05 mmol/l). The most impressive effect was observed after a repeated application of this combination at a distance of 7 days. Both the hyperglycaemia and the application of spores have a high tumour selectivity and a relatively good compatibility. The consequence for estimations of the LDH-, ALAT- and ASAT-activity in the judgment of the therapeutical tumours damage rate is discussed.
K Hambsch, and
C Körner, and
R Ludewig
January 1974,
Archiv fur Geschwulstforschung,
K Hambsch, and
C Körner, and
R Ludewig
March 1954,
Arztliche Forschung,
K Hambsch, and
C Körner, and
R Ludewig
December 1951,
Cancer research,
K Hambsch, and
C Körner, and
R Ludewig
April 1954,
Journal of bacteriology,
K Hambsch, and
C Körner, and
R Ludewig
December 1965,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale,
K Hambsch, and
C Körner, and
R Ludewig
January 1949,
The Biochemical journal,
K Hambsch, and
C Körner, and
R Ludewig
January 1974,
Archiv fur Geschwulstforschung,
K Hambsch, and
C Körner, and
R Ludewig
January 1963,
Radiobiologia, radiotherapia,
K Hambsch, and
C Körner, and
R Ludewig
January 1954,
Archiv fur Geschwulstforschung,
K Hambsch, and
C Körner, and
R Ludewig
January 1972,
Archiv fur Geschwulstforschung,
