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The distribution of the newly characterized peptide somatostatin-28(1-12) was determined in rat tissues using a radioimmunoassay in which the immune plasma is directed against the C-terminus of the dodecapeptide. In the central nervous system, somatostatin-28(1-12)-like immunoreactivity is highly concentrated in the hypothalamus and the amygdala. In the digestive system, the highest levels of immunoreactivity are found in the stomach, the pancreas and the colon. The immunoreactive material measured in different tissues is the heterogenous: in addition to the dodecapeptide, two N-terminally extended somatostatin-28(1-12) peptides of 4,400 and 8,000 mol wt are also detected by the immune plasma. However, the dodecapeptide itself usually accounts for the majority (66 to 75%) of the total somatostatin-28(1-12)-like immunoreactivity present in those tissues.
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
June 1991,
Neuropeptides,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
September 1990,
Brain research,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
March 1986,
Brain research,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
November 1983,
The Journal of clinical endocrinology and metabolism,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
May 1985,
Endocrinology,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
November 1982,
The Tohoku journal of experimental medicine,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
December 1983,
The Journal of clinical investigation,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
September 1982,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
January 1998,
Journal of endocrinological investigation,
R Benoit, and
N Ling, and
C Bakhit, and
J H Morrison, and
B Alford, and
R Guillemin
December 1988,
Regulatory peptides,
