BIOMAT Database Logo BIOMAT Database Logo

A comparison of compound action potential and cochlear microphonic two-tone suppression in the guinea pig. 1982

M C Remond, and R V Harrison, and J P Legouix

Cochlear microphonics (CM) and compound action potentials (AP) were recorded simultaneously with differential electrodes in the basal turn of the guinea pig cochlea. When CM two-tone suppression (2TS) curves were compared to AP simultaneous masking curves, good correspondence was observed between CM and AP suppression effects. The relationship between the 10 dB bandwidths of CM and AP 2TS curves remained constant for each animal despite differences between animals resulting from natural variations. Under pathological conditions (acute cochlear hypoxia) both CM and AP two-tone suppression effects were greatly reduced or disappeared. These results can be taken as evidence that CM suppression and AP suppression are the products of a common underlying mechanism.

UI MeSH Term Description Entries
D009412 Nerve Fibers Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM. Cerebellar Mossy Fibers,Mossy Fibers, Cerebellar,Cerebellar Mossy Fiber,Mossy Fiber, Cerebellar,Nerve Fiber
D010470 Perceptual Masking The interference of one perceptual stimulus with another causing a decrease or lessening in perceptual effectiveness. Masking, Perceptual,Maskings, Perceptual,Perceptual Maskings
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D003055 Cochlear Microphonic Potentials The electric response of the cochlear hair cells to acoustic stimulation. Cochlear Microphonic Potential,Potential, Cochlear Microphonic,Potentials, Cochlear Microphonic
D003056 Cochlear Nerve The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing. Acoustic Nerve,Auditory Nerve,Acoustic Nerves,Auditory Nerves,Cochlear Nerves,Nerve, Acoustic,Nerve, Auditory,Nerve, Cochlear,Nerves, Acoustic,Nerves, Auditory,Nerves, Cochlear
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D006198 Hair Cells, Auditory Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the COCHLEA. Towards the cochlear apex, the length of hair cell bodies and their apical STEREOCILIA increase, allowing differential responses to various frequencies of sound. Auditory Hair Cells,Cochlear Hair Cells,Auditory Hair Cell,Cell, Cochlear Hair,Cells, Cochlear Hair,Cochlear Hair Cell,Hair Cell, Auditory,Hair Cell, Cochlear,Hair Cells, Cochlear
D000200 Action Potentials Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli. Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

M C Remond, and R V Harrison, and J P Legouix
The effects of histamine and its antagonists on the cochlear microphonic and the compound action potential of the guinea pig.
August 2001, Auris, nasus, larynx,
M C Remond, and R V Harrison, and J P Legouix
Two-tone interactions in the cochlear microphonic.
September 1982, Hearing research,
M C Remond, and R V Harrison, and J P Legouix
Studies of two-tone interaction as seen in the guinea pig microphonic.
November 1968, The Journal of the Acoustical Society of America,
M C Remond, and R V Harrison, and J P Legouix
Cochlear microphonic enhancement in two tone interactions.
February 1991, Hearing research,
M C Remond, and R V Harrison, and J P Legouix
Corresponding effects of hypoxia on the cochlear microphonic and the compound action potential.
January 1982, Hearing research,
M C Remond, and R V Harrison, and J P Legouix
Postactivation potentiation of guinea pig cochlear microphonic potentials.
January 1971, Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove,
M C Remond, and R V Harrison, and J P Legouix
Changes in distortion of two-tone cochlear microphonic and otoacoustic emission signals during an acute endolymphatic hydrops in the guinea pig.
May 2006, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
M C Remond, and R V Harrison, and J P Legouix
Corresponding effects of acoustic fatigue on the cochlear microphonic and the compound action potential.
January 1982, Hearing research,
M C Remond, and R V Harrison, and J P Legouix
Comparison of sound-transmission and cochlear-microphonic characteristics in Mongolian gerbil and guinea pig.
January 1977, The Journal of the Acoustical Society of America,
M C Remond, and R V Harrison, and J P Legouix
Analysis of compound action potential responses to tone bursts in the human and guinea pig cochlea.
November 1976, The Journal of the Acoustical Society of America,
Copied contents to your clipboard!