-transparent.png){kind=logo}
Transmission computed tomography (CT) was used to study the global and regional density changes in the dog lung associated with oleic acid induced lung injury. The same level of the lower thorax was scanned (5 s/scan) during suspended ventilation at functional residual capacity prior to and after oleic acid infusion (0.05 ml/kg) into the right atrium. The first signs of edema were usually seen within 15 to 30 min after oleic acid infusion and consisted of patchy areas of increased density primarily in the peripheral and dependent zones. Mean CT density (Hounsfield units + 1,000) of lung cross sections from five dogs was 198 +/- 9 (SEM) during base line; density significantly (p less than 0.05) increased to 243 +/- 14 30 min after infusion and reached an apparent plateau of 294 +/- 31 75 min after oleic acid infusion. Thermal-dye dilution measurements indicated that extravascular lung water increased by 3.8 ml/kg from base line to 75 min after oleic acid infusion.
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
August 1993,
International journal of experimental pathology,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
February 2004,
American journal of respiratory and critical care medicine,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
June 1980,
Journal of applied physiology: respiratory, environmental and exercise physiology,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
November 1996,
Physiological measurement,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
June 2001,
Radiology,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
July 2002,
Critical care medicine,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
September 1987,
Masui. The Japanese journal of anesthesiology,
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
July 1990,
Journal of applied physiology (Bethesda, Md. : 1985),
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
April 1997,
Journal of applied physiology (Bethesda, Md. : 1985),
L W Hedlund, and
E L Effmann, and
W M Bates, and
J W Beck, and
P L Goulding, and
C E Putman
September 1981,
Hiroshima journal of medical sciences,
