Biomaterial Database

Cross resistance between Ascaris suum and Nippostrongylus brasiliensis in mice. 1982

L Eriksen

The present study shows that N. brasiliensis infection in thymus-bearing mice results in resistance against a subsequent A. suum infection. In contrast thymus-deficient mice do not develop this heterologous resistance. Thymus-deficient mice, on the other hand, develop resistance to homologous challenge although to a lesser degree than thymus-bearing mice. Further, it is shown that A. suum infection in thymus-bearing mice yields resistance against a subsequent N. brasiliensis infection. The underlying mechanism of the cross resistance between A. suum and N. brasiliensis in mice may be both shared antigens and tissue reactions such as fibrosis and macrophage activation.

UI	MeSH Term	Description	Entries
D009349	Nematode Infections	Infections by nematodes, general or unspecified.	Infections, Nematode,Infection, Nematode,Nematode Infection
D009559	Nippostrongylus	A genus of intestinal nematode parasites belonging to the superfamily HELIGMOSOMATOIDEA, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits. Infection is usually through the skin.	Rat Nematode,Nematode, Rat,Nematodes, Rat,Rat Nematodes
D003429	Cross Reactions	Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.	Cross Reaction,Reaction, Cross,Reactions, Cross
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001196	Ascariasis	Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.	Ascaris Infection,Ascariases,Ascaris Infections,Infection, Ascaris,Infections, Ascaris
D001200	Ascaris	A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.	Ascari
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus