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Attempts were made to evaluate the separate effect on kidney function of immunosuppressive treatment (IS) and plasma exchange (PE) in 27 patients with rapidly progressive glomerulonephritis (RPGN). Twenty-four of the patients were treated with PE. Initial IS was supplemented with PE within 6-12 days in 5 patients, and after at least 14 days in 13. Because of suspected septicemia, 2 patients were first treated with PE, and IS was not initiated until the possibility of septicemia had been excluded. In 4 severely ill patients wih rapid clinical deterioration, both treatments were started simultaneously. Twenty patients improved during one or both treatments, 4 with IS alone, 2 with IS and doubtfully with PE, 3 with IS and probably also with PE, 5 both with IS and PE and one with PE alone. In 5 patients the individual effects of IS and PE could not be evaluated. In another 2 patients the combined treatment seemed to influence the course favourably. In the remaining 7 patients the effect of the treatment was doubtful or nil. Two further patients with Goodpasture's syndrome were treated. They were admitted late, and both kinds of treatment were instituted simultaneously. One of them died in respiratory insufficiency, the other remained oliguric while the pulmonary changes faded. Thus, PE added a positive effect to IS in several patients with RPGN. The treatment had few and mostly mild side-effects.
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
January 1989,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
January 2013,
Contributions to nephrology,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
January 1990,
Progress in clinical and biological research,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
January 1988,
Clinical nephrology,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
August 1997,
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
November 1984,
British medical journal (Clinical research ed.),
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
January 1985,
Life support systems : the journal of the European Society for Artificial Organs,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
November 1981,
Deutsche medizinische Wochenschrift (1946),
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
July 1983,
The International journal of artificial organs,
H Thysell, and
P Bygren, and
U Bengtsson, and
T Lindholm, and
M Norlin, and
M Jonsson, and
C Brun, and
S Larsen, and
F Jørgensen, and
A Sjöholm, and
A B Laurell
June 1982,
Die Medizinische Welt,
