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The ability of platelet microsomes to generate platelet aggregating activity on addition of arachidonic acid was evaluated in women taking oral contraceptives and in controls taking no medication but matched for age, sex, and family history. Oral contraceptive users generated significantly more platelet aggregating activity per 100 ug of platelet microsomal protein than controls. Variation in generation of platelet aggregating activity during the menstrual cycle was also observed with highest activity during the third week. These studies show an altered balance of platelet prostaglandin and thromboxane synthesis in oral contraceptive users which may contribute to their increased incidence of thromboembolic phenomena.
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
January 1981,
Hormone and metabolic research. Supplement series,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
February 2001,
Atherosclerosis,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
November 1981,
British journal of haematology,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
December 1978,
British journal of pharmacology,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
June 1980,
The Journal of laboratory and clinical medicine,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
November 1983,
British medical journal (Clinical research ed.),
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
February 1996,
Thrombosis research,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
April 1996,
Atherosclerosis,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
January 1978,
Advances in prostaglandin and thromboxane research,
A E Schorer, and
J M Gerrard, and
J G White, and
W Krivit
January 1985,
Wiener klinische Wochenschrift,
