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Pulmonary microembolization was induced by infusion of thrombin during inhibition of the fibrinolytic system. After embolization cardiac output decreased, pulmonary vascular resistance and pulmonary arterial pressure increased. There was a transient decrease in PaO2. Immediately after embolization there was an increased permeability indicated by tremendous increase in lymph flow with a constant lymph/plasma protein ratio. The lymph/plasma ratio for hemoglobin and for FITC-Dextran (mw 150 000) also increased indicating leakage of large molecules. The increased permeability was accompanied by a significant increase in extra-vascular lung-water as measured both with the thermal conductivity and the dry/wet weight method.
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
November 1967,
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B Risberg, and
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W R Webb
January 1989,
Circulation research,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
January 1948,
Transactions of the American Clinical and Climatological Association,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
November 1958,
Surgery, gynecology & obstetrics,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
October 1986,
The American review of respiratory disease,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
January 1972,
Bulletin de la Societe internationale de chirurgie,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
January 1990,
Progress in clinical and biological research,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
January 1963,
Dermatologica,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
March 1956,
Minerva medica,
B Risberg, and
K Osburn, and
K Pilgreen, and
S D Wax, and
W R Webb
June 1956,
The Tohoku journal of experimental medicine,
