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The bioavailability of quinidine sulfate after oral administration of a commercial sustained-release quinidine tablet was compared with that of oral quinidine sulfate solution in 18 normal subjects. Three hundred milligrams of each product was administered to each subject in standard cross-over fashion on separate occasions, with plasma quinidine levels measured for 46 h after each dose. Although peak plasma quinidine levels were lower, and occurred later, after tablet administration than after solution, analysis of the area under the plasma quinidine level-time curve (AUC) values for each product indicated that the products were equivalent, in terms of the extent of absorption, with the mean AUC (0-46 h) value for the tablet, 8744 . 4 ng x h ml-1, comparable to that of the solution, 9145 . 9 ng x h ml-1.
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
January 1982,
Clinical pharmacy,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
October 1978,
Journal of pharmaceutical sciences,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
January 1990,
Biopharmaceutics & drug disposition,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
November 1987,
Arerugi = [Allergy],
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
October 1974,
Clinical pharmacology and therapeutics,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
January 1983,
Clinical therapeutics,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
August 1979,
European journal of clinical pharmacology,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
August 1987,
Clinical pharmacokinetics,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
April 1986,
International journal of clinical pharmacology, therapy, and toxicology,
W T Sawyer, and
C C Pulliam, and
A Mattocks, and
J Foster, and
B W Hadzija, and
H M Rosenthal
August 2004,
The Medical journal of Malaysia,
