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Enterochromaffin cells (EC) from the cat duodenum were studied before and after electrical efferent stimulation of the cervical vagi by means of electron microscopy and fluorescence histochemistry according to the Hillarp-Falck technique. From the same animals portal blood plasma was assayed for serotonin (5-HT) at various stages of the nerve stimulation. Within 15 min after the onset of vagal nerve stimulation there was a more than twofold increase of the portal 5-HT levels, which returned to normal after cessation of stimulation. There was also a pronounced reduction in the fluorescence intensity of EC demonstrating a lowered intracellular 5-HT level. Ultrastructurally there was evidence for basal exocytosis as well as for a release of osmiophilic material from the EC directly into the gut lumen after nerve stimulation. Together, these observations strongly suggest a vagally induced 5-HT release from EC in the cat.
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
November 1976,
Acta physiologica Scandinavica,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
November 1968,
Acta physiologica Scandinavica,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
October 1953,
Nature,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
January 2007,
The Analyst,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
July 1976,
Acta physiologica Scandinavica,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
June 1957,
The Journal of experimental medicine,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
January 1996,
Behavioural brain research,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
March 1968,
Gastroenterology,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
July 2004,
Gastroenterology,
H Ahlman, and
H N Bhargava, and
P E Donahue, and
B Newson, and
T K Das Gupta, and
L M Nyhus
January 1955,
The Journal of pathology and bacteriology,
