-transparent.png){kind=logo}
Five patients with severe heart disease developed cardiogenic shock of more than 24 hours' duration. As a sequela to the shock, severe liver affection was demonstrated. Serum aspartate aminotransferases and serum lactate dehydrogenases showed very high activities. The prothrombin-proconvertin index was reduced to less than 25% of the normal. Four of the patients were jaundiced. The condition gave rise to some differential diagnostic problems. Liver biopsies were available from four of the patients, and histological examination of an autopsy specimen of the liver was performed in each case. The liver histology showed centrilobular necrosis and haemorrhage in all patients. It seems that centrilobular fibrosis develops later in the condition. The pathogenesis of this liver affection is probably hypoxic injury to the centrilobular areas of the liver lobule due to reduced liver blood flow.
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
August 1971,
Zeitschrift fur Erkrankungen der Atmungsorgane mit Folia bronchologica,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
January 1993,
Journal of gastroenterology and hepatology,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
December 1984,
Orvosi hetilap,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
July 2010,
The Laryngoscope,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
March 1950,
The American journal of pathology,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
August 1972,
Orvosi hetilap,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
October 1979,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
July 1982,
Ugeskrift for laeger,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
April 2004,
The American journal of surgical pathology,
H S Birgens, and
J Henriksen, and
P Matzen, and
H Poulsen
May 1976,
New York state journal of medicine,
