Mucoepidermoid and acini cel carcinoma of the salivary glands are relatively rare and have a tendency to recur locally and sometimes metastasize to lymph nodes and at a distance. Such an evolution is difficult to predict even if one uses anatomo-pathological criteria, which explains the uncertain prognostic of these neoplasms and the difficulty encountered in establishing their therapy. Seven cases of mucoepidermoid carcinoma and five cases of acinic cell carcinoma are reported with statistical, clinical, and anatomo-pathological data. The evolution of these tumors are studied according to the therapy used, which leads us to establish a therapeutic protocol.