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147 colon and/or rectum cancer patients in all clinical stages (according to TNM classification) aged 34 to 71 years were studied before radical surgery and 14, 45 and 90 days after it. The in vitro cell-mediated immunity was evaluated using the blastogenic transformation of blood lymphocytes to phytohemagglutinin (PHA), fast and total E rosettes. The immunosuppression observed in all clinical stages in comparison to donors becomes deeper 14 days after operation. 45 and 90 days after operation all three parameters studied increase but only in the clinical stage II (localized disease), the values reach and even surpass their initial level. Based on the obtained data conclusions were made in regard to the correlation of the lymphocyte functions to the clinical stage. In the localized (disseminated) stages a good (bad) ability of the immune system to recover is suggested.
R Markova, and
R Argirova, and
M Boeva
January 1979,
Minerva nefrologica,
R Markova, and
R Argirova, and
M Boeva
May 1979,
Pneumonologia polska,
R Markova, and
R Argirova, and
M Boeva
June 1972,
Gut,
R Markova, and
R Argirova, and
M Boeva
August 1981,
Neurology,
R Markova, and
R Argirova, and
M Boeva
November 1994,
Molecular and cellular endocrinology,
R Markova, and
R Argirova, and
M Boeva
January 2012,
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti,
R Markova, and
R Argirova, and
M Boeva
January 1984,
Progress in clinical and biological research,
R Markova, and
R Argirova, and
M Boeva
October 1982,
Acta ophthalmologica,
R Markova, and
R Argirova, and
M Boeva
September 1982,
Mycopathologia,
R Markova, and
R Argirova, and
M Boeva
June 1982,
European journal of cancer & clinical oncology,
