-transparent.png){kind=logo}
The effect of two weeks of lithium (Li) pretreatment on up and down regulation of muscarinic receptors in rat brain was measured in two groups of rats. After two weeks of feeding 0.2% LiCL in ground pellets, one group of rats was injected with atropine (3 mg/kg daily for 5 days) and another group with diisopropyl fluorophosphate, a cholinesterase inhibitor (1.2 mg/kg). Li pretreatment completely abolishes the significant 23% rise in QNB binding induced by atropine but does not prevent the significant 16% decline in QNB binding induced by DFP. These results suggest that chronic Li pretreatment prevents supersensitivity but does not prevent subsensitivity of rat brain muscarinic receptors.
A Levy, and
J Zohar, and
R H Belmaker
June 1994,
Neuroscience letters,
A Levy, and
J Zohar, and
R H Belmaker
December 1994,
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao,
A Levy, and
J Zohar, and
R H Belmaker
January 1986,
Neurochemistry international,
A Levy, and
J Zohar, and
R H Belmaker
August 1987,
Journal of neurochemistry,
A Levy, and
J Zohar, and
R H Belmaker
January 1988,
Neurochemistry international,
A Levy, and
J Zohar, and
R H Belmaker
November 1989,
Molecular pharmacology,
A Levy, and
J Zohar, and
R H Belmaker
January 1990,
Biochemistry international,
A Levy, and
J Zohar, and
R H Belmaker
December 1996,
Alcoholism, clinical and experimental research,
A Levy, and
J Zohar, and
R H Belmaker
January 1992,
Clinical neuropharmacology,
A Levy, and
J Zohar, and
R H Belmaker
September 1973,
Psychopharmacologia,
