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A double-blind study was performed on 20 patients comparing the safety and efficacy of Iopamidol and Metrizamide in cervical myelography. The radiographic qualities of the Iopamidol and Metrizamide examinations were equivalent when using the same volume (12 to 13 ml), concentration (200 mg I/ml), and a C1-2 route of administration. The performance of a CT scan on selected patients in specified areas of interest provided additional diagnostic information in some patients (e.g syringomyelia, degenerative spondylosis). The adverse reactions were mild in the Iopamidol group with 4 of the 10 patients experiencing no adverse reactions. The more severe reactions, including disorientation, agitation, dysarthria, asterixis, hyperreflexia and EEG abnormalities were limited to the Metrizamide group with one or more occurring in 2 of the 10 patients studied. Only one Metrizamide patient experienced no adverse reactions. In this study containing a limited number of patients, Iopamidol was shown to be a diagnostically effective and safer contrast medium for performing cervical myelography.
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
May 1986,
Rontgenpraxis; Zeitschrift fur radiologische Technik,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
October 1984,
AJR. American journal of roentgenology,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
April 1983,
Journal of neurosurgery,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
September 1985,
The British journal of radiology,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
June 1988,
Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
June 1988,
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
January 1985,
AJNR. American journal of neuroradiology,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
September 1984,
Journal of the Canadian Association of Radiologists,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
October 1988,
The British journal of radiology,
B P Drayer, and
M A Warner, and
A Sudilovsky, and
J Luther, and
R Wilkins, and
S Allen, and
M Bates
January 1986,
Acta radiologica. Supplementum,
