-transparent.png){kind=logo}
28 adult patients with radiological evidence of medullary sponge kidney (MSK) were studied. Hypercalcemia and increased serum parathyroid hormone (PTH) values were found in 10 patients (36%). In 7 of them, parathyroid surgery was performed: a single adenoma was found in 6 cases and multiple-gland hyperplasia in 1 case. After surgery, 3 patients had normalization of calcium metabolism; 4 patients had persistence of hypercalciuria with progressive increase in serum PTH values (and recurrence of the adenoma in 1 case). Of the remaining patients, 10 (36%) had definite or marginal hypercalciuria, resulting from renal calcium leak in 8 and from intestinal calcium hyperabsorption in 2 of them. In 8 patients (28%), no evidence of disordered calcium metabolism was found. The association of MSK and hyperparathyroidism is not a chance occurrence. MSK might be a renal anatomical complication of primary hyperparathyroidism, or it might be regarded as an anatomic substrate--or rather as a consequence--of prolonged hypercalciuria, regardless of its pathogenesis. The lack of disordered calcium metabolism in a considerable number of patients, however, shows that the enigma of MSK is still far from being solved.
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
February 1988,
Urology,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
October 1977,
JAMA,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
July 1977,
JAMA,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
February 1977,
JAMA,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
April 1968,
British journal of urology,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
March 1983,
Gaceta medica de Mexico,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
July 2018,
Journal of medical case reports,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
January 2014,
Case reports in urology,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
October 2018,
Journal of medical imaging and radiation oncology,
G Maschio, and
N Tessitore, and
A D'Angelo, and
A Fabris, and
A Corgnati, and
L Oldrizzi, and
C Loschiavo, and
A Lupo, and
E Valvo, and
L Gammaro, and
C Rugiu
January 1971,
Ugeskrift for laeger,
