-transparent.png){kind=logo}
Effects of lysozyme(LY) alone and combination with various antitumor agents were examined using syngeneic tumors mainly Meth-A and MH 134 transplanted into Balb/c and C3H/He mice, respectively. The effects of LY on pulmonary metastases were also examined in BDF1 mice bearing Lewis lung carcinoma (3LL). LY inhibited the growth of Meth-A tumor and enhanced antitumor effects of mitomycin C (MMC). bleomycin (BLM) and 5-fluorouracil (5-FU), LY activated antitumor effects of MMC, BLM and 5-FU on MH 134 tumor, however, LY alone did not show any significant antitumor effect on it. The combination treatments using LY with MMC or 5-FU showed a marked inhibition on pulmonary metastases of 3LL. The pre-treatment of LY inhibited the tumor growth of Sarcoma-180 in ICR mice.
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
June 1946,
American review of Soviet medicine,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
September 1965,
Antibiotiki,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
January 1987,
Nihon Sanka Fujinka Gakkai zasshi,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
January 2006,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
January 1983,
Acta Academiae Medicinae Wuhan = Wu-han i hsueh yuan hsueh pao,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
March 1964,
The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
June 1977,
Tsurumi shigaku. Tsurumi University dental journal,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
January 1958,
Antibiotiki,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
August 1992,
Gan to kagaku ryoho. Cancer & chemotherapy,
K Fukawa, and
N Nishimura, and
O Irino, and
K Nakazato, and
A Taguchi, and
K Nitta
October 2001,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
