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To evaluate further the metabolic capacity of psoriatics, the activities and inducibility of aryl hydrocarbon hydroxylase (AHH) were measured in cultured mitogen-stimulated lymphocytes from the peripheral blood of 68 psoriatic and 39 control patients. There was no significant difference in the mean basal and induced AHH activities between the psoriatics and the controls, although the former showed a slight tendency towards a higher inducibility ratio. In both, the basal and induced AHH values decreased significantly with increasing age. The cigarette smokers in both groups had significantly higher AHH activities than the nonsmokers. Antipsoriatic treatment (Anthralin, PUVA) did not seem to influence the lymphocyte AHH activities. No association was demonstrable between the AHH activities and the duration of the disease.
N T Kärki, and
J Karvonen, and
O Pelkonen
January 1982,
Toxicology,
N T Kärki, and
J Karvonen, and
O Pelkonen
September 1978,
American journal of human genetics,
N T Kärki, and
J Karvonen, and
O Pelkonen
February 1979,
Lancet (London, England),
N T Kärki, and
J Karvonen, and
O Pelkonen
August 1976,
Biochemical genetics,
N T Kärki, and
J Karvonen, and
O Pelkonen
June 1977,
Cancer research,
N T Kärki, and
J Karvonen, and
O Pelkonen
May 1976,
Biochemical and biophysical research communications,
N T Kärki, and
J Karvonen, and
O Pelkonen
January 1979,
Journal of environmental pathology and toxicology,
N T Kärki, and
J Karvonen, and
O Pelkonen
November 1978,
Cancer research,
N T Kärki, and
J Karvonen, and
O Pelkonen
July 1973,
Cancer research,
N T Kärki, and
J Karvonen, and
O Pelkonen
July 1981,
Cancer research,
