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We have carried out a survey to determine the prevalence of carriers of pyruvate kinase deficiency haemolytic anaemia in Basenjis in Victoria. Of 186 dogs tested, 20 were found to be carriers for pyruvate kinase deficiency, a prevalence similar to that reported overseas. Of the 20 carriers found, 17 were born in Australia and were traced directly to 1 of the 3 imported carriers. Despite the relatively high frequency of carriers, no mating of 2 carriers has yet been detected and no dogs with haemolytic anaemia have been observed. The inheritance of the pyruvate kinase deficiency has been traced through up to 5 generations of dogs in Australia and is consistent with co-dominance for pyruvate kinase activity and with an autosomal recessive gene for haemolytic anemia.
G G Hogg, and
B J Horton, and
H Brown
December 1972,
Journal of the American Veterinary Medical Association,
G G Hogg, and
B J Horton, and
H Brown
October 1982,
Australian veterinary journal,
G G Hogg, and
B J Horton, and
H Brown
December 1974,
American journal of veterinary research,
G G Hogg, and
B J Horton, and
H Brown
February 1976,
Respiration physiology,
G G Hogg, and
B J Horton, and
H Brown
October 1975,
The Tohoku journal of experimental medicine,
G G Hogg, and
B J Horton, and
H Brown
January 1977,
Animal blood groups and biochemical genetics,
G G Hogg, and
B J Horton, and
H Brown
January 1971,
Canadian journal of comparative medicine : Revue canadienne de medecine comparee,
G G Hogg, and
B J Horton, and
H Brown
January 1991,
Veterinary clinical pathology,
G G Hogg, and
B J Horton, and
H Brown
January 1997,
Human heredity,
G G Hogg, and
B J Horton, and
H Brown
October 1975,
American journal of veterinary research,
