[Precancerous lesions associated with atrophic chronic gastritis and gastric peptic ulcer]. 1982

A M Nogueira, and C S Barbosa, and D Miranda

Among the gastric lesions related to an increased risk for gastric cancer (precancerous conditions) two have deserved special attention, i.e., atrophic gastritis and peptic ulcer. In this paper the authors study the incidence of glandular dysplasia in atrophic gastritis and gastric peptic ulcer. In 148 cases of atrophic gastritis dysplastic lesions were diagnosed in 92 (62,0%): 63 cases (68,4%) with mild dysplasia, 25 cases (27,0%) with moderate dysplasia and 4 cases (4,3%) with severe dysplasia. In 329 gastric peptic ulcers examined there were 51 (15,5%) with dysplastic lesions: in 34 cases (66,6%) there was mild dysplasia, 12 cases (23,5%) moderate dysplasia and (9,8%) severe dysplasia. A prospective study with histological multiple sections from the stomach would be helpful for better understanding of these precancerous lesions.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011230 Precancerous Conditions Pathological conditions that tend eventually to become malignant. Preneoplastic Conditions,Condition, Preneoplastic,Conditions, Preneoplastic,Preneoplastic Condition,Condition, Precancerous,Conditions, Precancerous,Precancerous Condition
D005260 Female Females
D005756 Gastritis Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders. Gastritides
D005757 Gastritis, Atrophic GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis. Atrophic Gastritides,Atrophic Gastritis,Gastritides, Atrophic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013274 Stomach Neoplasms Tumors or cancer of the STOMACH. Cancer of Stomach,Gastric Cancer,Gastric Neoplasms,Stomach Cancer,Cancer of the Stomach,Gastric Cancer, Familial Diffuse,Neoplasms, Gastric,Neoplasms, Stomach,Cancer, Gastric,Cancer, Stomach,Cancers, Gastric,Cancers, Stomach,Gastric Cancers,Gastric Neoplasm,Neoplasm, Gastric,Neoplasm, Stomach,Stomach Cancers,Stomach Neoplasm
D013276 Stomach Ulcer Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). Gastric Ulcer,Gastric Ulcers,Stomach Ulcers,Ulcer, Gastric,Ulcer, Stomach,Ulcers, Gastric,Ulcers, Stomach

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