Differential scanning calorimetric measurements on human lenses. 1982

F A Bettelheim, and S Christian, and L K Lee

Differential scanning calorimetric measurements were performed between - 30 degrees C and 15 degrees C. The cortical sections of normal human lenses usually show one endotherm at the melting point, while the nucleus indicates a composite endotherm that can be separated into two endotherms with two melting points. Cataractous human lenses usually have composite endotherms from the cortical, intermediate as well as nuclear regions. We interpret the different endotherms as representing different kinds of freezable water contents: free water and partially bound water. Both in normal and cataractous human lenses, there is an appreciable amount of non-freezable water. The amount of non-freezable water is less in cataractous lenses than in normal lenses, indicating a syneretic process as a cause of cataract formation.

UI MeSH Term Description Entries
D007904 Lens Cortex, Crystalline The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance. Cortex, Crystalline Lens,Crystalline Lens Cortex
D007908 Lens, Crystalline A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION. Eye Lens,Lens, Eye,Crystalline Lens
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D001834 Body Water Fluids composed mainly of water found within the body. Water, Body
D002152 Calorimetry, Differential Scanning Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample. Differential Thermal Analysis, Calorimetric,Calorimetric Differential Thermal Analysis,Differential Scanning Calorimetry,Scanning Calorimetry, Differential
D002386 Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) Cataract, Membranous,Lens Opacities,Pseudoaphakia,Cataracts,Cataracts, Membranous,Lens Opacity,Membranous Cataract,Membranous Cataracts,Opacities, Lens,Opacity, Lens,Pseudoaphakias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012542 Scattering, Radiation The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Radiation Scattering,Radiation Scatterings,Scatterings, Radiation

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