Plasma cholinesterase activity in bank blood. 1980

H M Epstein, and D Jarzemsky, and L Zuckerman, and P Vagher

Plasma cholinesterase activity was periodically measured in bank blood. Of the initial plasma cholinesterase activity 87% was retained after 21 days of storage at 4 C in citrate-phosphate-dextrose solution. In addition, plasma frozen for 7 weeks at -70 C showed no decrease in enzyme activity. No difference could be demonstrated in the stability of the enzyme related to whether the blood was stored in citrate-phosphate-dextrose or in acid-citrate-dextrose solution. Bank blood transfusion prior to or during succinylcholine administration should not significantly alter the duration of action of succinylcholine, and would probably be effective in the management of prolonged apnea resulting from a deficiency of this enzyme.

UI MeSH Term Description Entries
D007275 Injections, Intravenous Injections made into a vein for therapeutic or experimental purposes. Intravenous Injections,Injection, Intravenous,Intravenous Injection
D008297 Male Males
D001771 Blood Banks Centers for collecting, characterizing and storing blood or plasma. Bank, Blood,Banks, Blood,Blood Bank
D001793 Blood Preservation The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism). Blood Preservations,Preservation, Blood,Preservations, Blood
D001803 Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D002802 Cholinesterases Acylcholineacylhydrolase,Cholase,Cholinesterase
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000768 Anesthesia, General Procedure in which patients are induced into an unconscious state through use of various medications so that they do not feel pain during surgery. Anesthesias, General,General Anesthesia,General Anesthesias
D001049 Apnea A transient absence of spontaneous respiration. Apneas

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