A crossover study comparing the kinetics of Tc-99m-labeled diethyl- and diisopropyl-IDA. 1980

M Hernandez, and L Rosenthall

Tc-99m-diisopropyl-IDA (DISIDA) and Tc-99m-diethyl-IDA (DE-IDA) were compared in each of 44 patients who had serum bilirubin levels ranging from normal to 50 mg/dl. Quantitative and qualitative analysis showed a significantly higher liver uptake relative to background for DISIDA. No significant differences between DISIDA and DE-IDA were found in the blood retention and rate of liver washout. Clinically, the diagnostic information received from both radiopharmaceuticals was essentially the same.

UI MeSH Term Description Entries
D007098 Imino Acids Carboxylic acids that contain an imino group (C Amino Acids, Secondary,Acids, Secondary Amino,Secondary Amino Acids,Acids, Imino
D007700 Kinetics The rate dynamics in chemical or physical systems.
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008107 Liver Diseases Pathological processes of the LIVER. Liver Dysfunction,Disease, Liver,Diseases, Liver,Dysfunction, Liver,Dysfunctions, Liver,Liver Disease,Liver Dysfunctions
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D005260 Female Females
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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