-transparent.png){kind=logo}
Mating or administration of morphine to female hamsters reliably decreases lateral displacement, a sensitive index of female sexual responsitivity. Morphine's effects are antagonized by naloxone. We asked whether endogenous opiates are significantly involved in the mating-induced inhibition of sexual responsitivity by testing whether naloxone or naltrexone attenuated the mating-induced decreases in lateral displacement. Naloxone (4 mg/kg) increased lateral displacement in only one of three tests in females before mating. Naloxone did not attenuate the mating-induced decreases in lateral displacement or lordosis behavior in either ovariectomized, hormonally supplemented or intact females. Large doses of naltrexone produced no reliable effects on sexual behavior during estrus in unmated females, nor did it attenuate the mating-induced decreases in sexual responding, regardless of the time of day of mating. Naloxone often increases the variability of sexual responding. We conclude that naloxone-sensitive mechanisms do not play a critical role in the expression of sexual behavior in female hamsters.
N L Ostrowski, and
R G Noble, and
L D Reid
January 1986,
Physiology & behavior,
N L Ostrowski, and
R G Noble, and
L D Reid
August 1996,
European journal of pharmacology,
N L Ostrowski, and
R G Noble, and
L D Reid
January 1990,
Physiology & behavior,
N L Ostrowski, and
R G Noble, and
L D Reid
April 1997,
The American journal of physiology,
N L Ostrowski, and
R G Noble, and
L D Reid
September 1986,
Behavioral and neural biology,
N L Ostrowski, and
R G Noble, and
L D Reid
December 1978,
Hormones and behavior,
N L Ostrowski, and
R G Noble, and
L D Reid
December 1988,
Hormones and behavior,
N L Ostrowski, and
R G Noble, and
L D Reid
June 1983,
Hormones and behavior,
N L Ostrowski, and
R G Noble, and
L D Reid
July 1975,
Journal of comparative and physiological psychology,
N L Ostrowski, and
R G Noble, and
L D Reid
September 1984,
Pharmacology, biochemistry, and behavior,
