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During intra-abdominal surgery, plasma levels of norepinephrine in peripheral venous blood were higher in 11 patients who received fentanyl-nitrous oxide-oxygen than in 10 patients who received enflurane-nitrous oxide-oxygen [703 +/- 95 vs 463 +/- 38 (SEM) pg/ml]. At the same time, systolic blood pressure (143 +/- 6 vs 121 +/- 4 torr), mean blood pressure (108 +/- 4 vs 98 +/- 3 torr), and pulse rate (87 +/- 3 vs 98 +/- 4 beats per minute) also differed significantly (p less than 0.05); plasma levels of epinephrine (235 +/- 61 vs 113 +/- 21) did not. These values did not differ significantly between the two groups before induction of anesthesia, after induction but before skin incision, or in the recovery room. These data support the concept that enflurane anesthesia blocks the sympathetic response to surgical stress more effectively than low dose fentanyl anesthesia.
F F Brown, and
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P E Cryer
September 1984,
Anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
December 1985,
Masui. The Japanese journal of anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
November 1992,
Masui. The Japanese journal of anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
July 1987,
Anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
May 1986,
Masui. The Japanese journal of anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
January 1989,
Anesthesia and analgesia,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
March 1957,
The Journal of pharmacology and experimental therapeutics,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
December 1988,
Ma zui xue za zhi = Anaesthesiologica Sinica,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
April 1983,
Anesthesiology,
F F Brown, and
W D Owens, and
J A Felts, and
E L Spitznagel, and
P E Cryer
October 1984,
Masui. The Japanese journal of anesthesiology,
