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43 patients with metastasizing sarcomas were treated with a combination of either vincristin, adriamycin and cis-platinum (n = 21) or ifosfamide and cis-platinum at three weeks' intervals in each case. Ten patients responded to the first combination and nine to the second combination with objective tumor regression. Particularly the latter result is remarkable since 16 of the 22 patients had already been pretreated with combinations containing adriamycin. Obviously the combination of ifosfamide and cis-platinum is a promising alternative in metastasizing sarcomas of the bones and soft tissue, especially if the CYVADIC combination--which is often regarded as standard treatment--remained unsuccessful. This has no bearing on additional surgical measures or on radiotherapy which may be necessary in some patients.
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
January 1976,
Archiv fur Geschwulstforschung,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
June 1977,
Lijecnicki vjesnik,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
January 1980,
Chirurgisches Forum fur experimentelle und klinische Forschung,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
January 1989,
Cancer treatment and research,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
September 1974,
Revista medica de Chile,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
June 1982,
La Nouvelle presse medicale,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
January 1982,
Langenbecks Archiv fur Chirurgie,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
October 1980,
Journal de radiologie,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
April 1982,
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca,
W Bierbaum, and
K Bremer, and
N Firusian, and
M Higi, and
N Niederle, and
M E Scheulen, and
C G Schmidt, and
S Seeber
January 1974,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
