[Maternal blood flow in the human placenta (author's transl)]. 1982

T Beck

The intervillous microcirculation in the human placenta is still a subject of debate. This paper aims to establish whether or not a division of the human placenta into flow units - the "placentons" of Schuhmann et al. (1971, 1976) - is morphologically conceivable, and what pathways exist for the maternal blood flow through the intervillous space. The findings are compared with flow models published in the literature, and are discussed. Spiral arterial punctures were performed in 22 fresh placentas from term births using Wigglesworth's procedure, and the intervillous space was filled with Microfil. In five other placentas the fetal villi were also contrasted with Micropaque and gelatine. Six control placentas, which were not filled with contrast medium, served to eliminate the possibility of filling artefacts. Plain radiographs in choriobasal projection, lateral films of the lamillarly dissected injection regions and histologic serial sections documented the pathways followed by the contrast medium. The human placenta can be divided into flow units: each fetal cotyledon can be shown to be supplied by a maternal spiral artery. Within the flow units, flow is routed through arterial, capillary and venous areas can be clearly identified. They were also demonstrated in the control placentas, which were not filled with contrast medium.

UI MeSH Term Description Entries
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D008833 Microcirculation The circulation of the BLOOD through the MICROVASCULAR NETWORK. Microvascular Blood Flow,Microvascular Circulation,Blood Flow, Microvascular,Circulation, Microvascular,Flow, Microvascular Blood,Microvascular Blood Flows,Microvascular Circulations
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002824 Chorionic Villi Threadlike vascular projections of the chorion. Chorionic villi may be free or embedded within the DECIDUA forming the site for exchange of substances between fetal and maternal blood (PLACENTA). Placental Villi,Labyrinth of the Placenta,Labyrinthine Placenta,Placental Labyrinth Layer,Chorionic Villus,Labyrinth Layer, Placental,Placental Labyrinth Layers,Placental Villus,Villi, Chorionic,Villi, Placental,Villus, Chorionic,Villus, Placental
D003287 Contrast Media Substances used to allow enhanced visualization of tissues. Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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