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Urine samples from 176 healthy women between 29th and 40th week of gestation were analyzed by a test kit. Estrotec Slide Test, which offers a simple and fast test performance for estriol in pregnancy urine. The mechanism of this test system is based on a competitive latex agglutination inhibition reaction. The correlation between Estrotec Slide Test and estriol levels assayed in the same urine samples by a chemical method was r = 0,83. Variation of estriol determinations from urine and estriol levels in serum samples of women at the end of gestation measured by a radioimmunologic method was about 20% for all test principles examinated. The Estrotec Slide Test was proved to be a fast, semiquantitative method. The simple assay procedure itself imposes limits to the information available from it.
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