For 30 patients affected by obliterating arteriopathy in lower limbs, the use was made of an antithrombophilic complex of the arterial wall (aorta) consisting of both anti-coagulating and fybrinolytic principles. The results obtained, as regards both subjective and objective symptomatology, clearly showed a considerable increase in the hematic flow in the limbs affected by arteriopathy. Also the flow of the collateral circulation was improved. At the same time, a meaningful reduction in the abnormal cholesterol values was found. The preparation showed no antigenic activity. As or the oral administration, this preparation proved to be an effective one. Tolerance was completely satisfactory.