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First reports about incongruous H-Y antigen status in male-to-female and female-to-male transsexuals have been published by us in 1979. Meanwhile H-Y antigen expression was analyzed with the cytotoxicity assay of Goldberg et al. in 61 transsexuals. In 55 cases H-Y antigen status was found discordant with the anatomical, chromosomal and hormonal sex and corresponded to the gender identity of transsexuals. The relative frequency was 0,91. In 33 male-to-female transsexuals 29 were H-Y negative, one was intermediate, three were H-Y positive. In 28 female-to-male transsexuals 25 were H-Y positive, one was intermediate, two were H-Y negative. The new findings of an incongruous H-Y antigen status in genuine transsexuals may lead to new considerations about the pathogenesis of the disease and about the function of H-Y antigen.
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
January 1981,
L'Encephale,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
December 1982,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
June 1987,
Asian Pacific journal of allergy and immunology,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
January 1988,
Sudebno-meditsinskaia ekspertiza,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
August 1979,
The New England journal of medicine,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
January 1978,
Hormone research,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
January 1984,
Transplantation,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
March 1986,
Cell,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
March 1979,
British medical journal,
W Eicher, and
M Spoljar, and
J D Murken, and
K Richter, and
H Cleve, and
S Stengel-Rutkowski
April 1979,
British medical journal,
