[Synthesis and properties of substituted amides of 2H-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid]. 1978

V P Chernykh, and V I Gridasov

UI MeSH Term Description Entries
D008297 Male Males
D003499 Cyclic S-Oxides Heterocyclic S-Oxides,Cyclic S Oxides,Heterocyclic S Oxides,Oxides, Cyclic S,S Oxides, Cyclic,S-Oxides, Cyclic,S-Oxides, Heterocyclic
D004232 Diuretics Agents that promote the excretion of urine through their effects on kidney function. Diuretic,Diuretic Effect,Diuretic Effects,Effect, Diuretic,Effects, Diuretic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001581 Benzothiadiazines Heterocyclic compounds of a ring with SULFUR and two NITROGEN atoms fused to a BENZENE ring. Members inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS.
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D049993 Sodium Chloride Symporter Inhibitors Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. Benzothiadiazine Diuretic,Potassium Depleting Diuretic,Sodium Chloride Cotransporter Inhibitor,Sodium Chloride Symporter Inhibitor,Thiazide Diuretic,Thiazide Sensitive NaCl Cotransporter Inhibitor,Benzothiadiazine Diuretics,Diuretics, Thiazide,Potassium Depleting Diuretics,Sodium Chloride Cotransporter Inhibitors,Thiazide Diuretics,Thiazide Sensitive NaCl Cotransporter Inhibitors,Depleting Diuretic, Potassium,Diuretic, Benzothiadiazine,Diuretic, Potassium Depleting,Diuretic, Thiazide,Diuretics, Benzothiadiazine,Diuretics, Potassium Depleting
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

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