BIOMAT Database Logo BIOMAT Database Logo

[Effect of proteolysis inhibitors on serum proteinase activity and its antitryptic activity in postischemic toxemia]. 1978

V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov

Parenteral administration to animals of the antikallikrein serum containing 200gamma/ml of antibodies to the pancreatic kallikrein (10 ml/kg), ingitryl (1.5 Un/kg) and of tracilol (10 000 Un/kg) exerts in post-ischemic toxemia an inhibiting effect on the protamine-splitting blood serum activity and does not affect the benzoylarginine-paranitroanilide rate of splitting. Changes of the blood serum ability to bind trypsin and manifestation of the protamine-splitting activity during the first 9 hours of observation are of an undulating nature and the changes of these characteristics are reciprocal.

UI MeSH Term Description Entries
D007116 Immunization, Passive Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER). Convalescent Plasma Therapy,Immunoglobulin Therapy,Immunotherapy, Passive,Normal Serum Globulin Therapy,Passive Antibody Transfer,Passive Transfer of Immunity,Serotherapy,Passive Immunotherapy,Therapy, Immunoglobulin,Antibody Transfer, Passive,Passive Immunization,Therapy, Convalescent Plasma,Transfer, Passive Antibody
D007511 Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. Ischemias
D007610 Kallikreins Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77). Kallikrein,Kininogenase,Callicrein,Dilminal,Kallidinogenase,Kalliginogenase,Kallikrein A,Kallikrein B',Kallikrein Light Chain,Kinin-Forming Enzyme,Padutin,alpha-Kallikrein,beta-Kallikrein,beta-Kallikrein B,Enzyme, Kinin-Forming,Kinin Forming Enzyme,Light Chain, Kallikrein,alpha Kallikrein,beta Kallikrein,beta Kallikrein B
D008297 Male Males
D010447 Peptide Hydrolases Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES. Peptidase,Peptidases,Peptide Hydrolase,Protease,Proteases,Proteinase,Proteinases,Proteolytic Enzyme,Proteolytic Enzymes,Esteroproteases,Enzyme, Proteolytic,Hydrolase, Peptide
D011479 Protamines A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692) Protamine,Protamine Sulfate,Protamine Chloride,Chloride, Protamine,Sulfate, Protamine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001586 Benzoylarginine Nitroanilide A chromogenic substrate that permits direct measurement of peptide hydrolase activity, e.g., papain and trypsin, by colorimetry. The substrate liberates p-nitroaniline as a chromogenic product. BAPNA,N-alpha-Benzoyl-DL-arginine-4-nitroanilide,Benzoylarginine Nitroanilide Monohydrochloride,Benzoylarginine Nitroanilide, (R)-Isomer,Benzoylarginine Nitroanilide, (S)-Isomer,Benzoylarginine Nitroanilide, Monosodium Salt, Monohydrochloride,N-Benzoylarginine-4-nitroanilide,N-Benzoylarginyl-4-nitroanilide,Monohydrochloride, Benzoylarginine Nitroanilide,N Benzoylarginine 4 nitroanilide,N Benzoylarginyl 4 nitroanilide,N alpha Benzoyl DL arginine 4 nitroanilide,Nitroanilide, Benzoylarginine
D014357 Trypsin A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4. Tripcellim,Trypure,beta-Trypsin,beta Trypsin
D014361 Trypsin Inhibitors Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds. Trypsin Inhibitor,Inhibitor, Trypsin,Inhibitors, Trypsin

Related Publications

V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
[Effect of proteolysis enzymes and their inhibitors on oxygen uptake by rat brain tissue and its antitryptic activity].
January 1981, Ukrainskii biokhimicheskii zhurnal (1978),
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
[Serum antitryptic activity in children].
August 1978, Pediatriia,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
[Serum antitryptic activity in acute appendicitis].
August 1984, Khirurgiia,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
Effect of modification of reactive lysine on antitryptic and antichymotryptic activity of proteinase inhibitor from cow colostrum.
December 1979, Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
Effect of envenomation on human serum alpha-2 macroglobulin & total antitryptic activity.
December 1985, The Indian journal of medical research,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
[Quantitative characteristics of serum antitryptic activity].
January 1977, Ukrains'kyi biokhimichnyi zhurnal,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
Acetaldehyde decreases the antitryptic activity of alpha 1-proteinase inhibitor.
January 1992, Alcohol (Fayetteville, N.Y.),
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
Studies on serum antitrypsin. Fourth report: Chemical nature of antitryptic activity of serum. II. Its symplextheory.
March 1951, The Tohoku journal of experimental medicine,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
[Antitryptic, antifibrinolytic and antiphlogistic activity of natural protease inhibitors].
February 1960, Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
V A Protsenko, and V Z Kharchenko, and V F Veselov, and I F Spitsyn, and I V Bogadel'nikov
Influence of modified corticosteroids on antitryptic activity of rat serum.
May 1958, Circulation research,
Copied contents to your clipboard!