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Postsynthetic changes in the enzyme and structural proteins play an important role in the mechanisms of ageing of the lens, when development of protein aggregates and -S-S- linking occurs. Protection of the free -SH groups through the glutathione peroxidase and glutathione reductase system is a prerequisite to avoid these phenomena. Investigations on these two enzymes in young and old bovine lens tissues showed that they are themselves subjected to age-dependent modifications. With increasing age, the specific activity decreases while a simultaneous increase in heat lability occurs. This means that in the course of postsynthetic processes the stability of the conformation decreases and that finally the catalytic properties are lost.
C Ohrloff, and
G Lange, and
O Hockwin
June 1995,
Cell biochemistry and function,
C Ohrloff, and
G Lange, and
O Hockwin
May 1967,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
C Ohrloff, and
G Lange, and
O Hockwin
January 1981,
Acta biologica et medica Germanica,
C Ohrloff, and
G Lange, and
O Hockwin
March 1977,
Annales de genetique,
C Ohrloff, and
G Lange, and
O Hockwin
March 1970,
Zeitschrift fur klinische Chemie und klinische Biochemie,
C Ohrloff, and
G Lange, and
O Hockwin
July 1994,
Experimental eye research,
C Ohrloff, and
G Lange, and
O Hockwin
September 1983,
The British journal of nutrition,
C Ohrloff, and
G Lange, and
O Hockwin
March 1998,
The British journal of nutrition,
C Ohrloff, and
G Lange, and
O Hockwin
July 1988,
The British journal of nutrition,
C Ohrloff, and
G Lange, and
O Hockwin
January 1984,
Current eye research,
