Biomaterial Database

[Topically applied thiabendazole in the treatment of creeping eruption (cutaneous helminthiasis) (author's transl)]. 1980

H Bardach

Two patients with creeping eruption (cutaneous helminthiasis) on the feet contracted during a vacation in Ceylon were treated successfully by topical application of thiabendazole 50% in a paste destined for oral use in veterinary medicine. The preparation was applied once daily under occlusive dressings. There was no skin irritation. Prompt healing occurred after 3 and 6 days respectively. Because systemic thiabendazole therapy is frequently associated with toxic side effects, topical application seems to be the treatment of choice for creeping eruption caused by nematodes.

UI	MeSH Term	Description	Entries
D007815	Larva Migrans	Infections caused by nematode larvae which never develop into the adult stage and migrate through various body tissues. They commonly infect the skin, eyes, and viscera in man. Ancylostoma brasiliensis causes cutaneous larva migrans. Toxocara causes visceral larva migrans.	Creeping Eruption,Cutaneous Larva Migrans,Larva Migrans, Cutaneous,Larva Migrans, Ocular,Ocular Larva Migrans,Dew Itch,Ground Itch,Creeping Eruptions,Dew Itchs,Eruption, Creeping,Eruptions, Creeping,Ground Itchs,Itch, Dew,Itch, Ground,Itchs, Dew,Itchs, Ground
D008297	Male		Males
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000287	Administration, Topical	The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.	Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D013188	Sri Lanka	Country in southern Asia, an island in the Indian Ocean, south of India. The capital is Colombo.	Ceylon
D013827	Thiabendazole	2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)	Tiabendazol,2-(4'-Thiazolyl)Benzimidazole,Mintesol,Mintezol,Omnizole,Thibendole