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Twenty-eight patients with spastic and obstructive vascular disease were treated with intravenous regional guanethidine (IRG). The drug was injected into the affected hand or foot in doses of 10 or 20 mg, respectively. Temperature and strain-gauge plethysmography curves of the extremity were recorded before treatment, and three to four times during the subsequent 10 days. The effects of IRG, as observed by clinical laboratory examinations, were good in 8 of 12 patients. But in patients suffering from Bürger's disease or from major vessel obstructive disease, the results were not as good. However, in most patients IRG proved beneficial in relieving pain, an effect which sometimes outlasted objective improvements. IRG treatment is a simple and safe method for prolonged chemical sympathectomy.
D Olshwang, and
G Beer, and
F Magora
January 1982,
Annales de chirurgie de la main : organe officiel des societes de chirurgie de la main,
D Olshwang, and
G Beer, and
F Magora
December 1991,
Clinical rheumatology,
D Olshwang, and
G Beer, and
F Magora
December 1982,
Revue du rhumatisme et des maladies osteo-articulaires,
D Olshwang, and
G Beer, and
F Magora
May 1988,
Cahiers d'anesthesiologie,
D Olshwang, and
G Beer, and
F Magora
July 1979,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
D Olshwang, and
G Beer, and
F Magora
May 1974,
Lancet (London, England),
D Olshwang, and
G Beer, and
F Magora
February 1942,
British medical journal,
D Olshwang, and
G Beer, and
F Magora
June 1974,
Lancet (London, England),
D Olshwang, and
G Beer, and
F Magora
June 1993,
Journal of hand surgery (Edinburgh, Scotland),
D Olshwang, and
G Beer, and
F Magora
May 1977,
Lancet (London, England),
