Biomaterial Database

Aortic cusp involvement causing severe aortic regurgitation in a case of relapsing polychondritis. 1981

G S Sohi, and A M Desai, and W W Ward, and N C Flowers

A case with relapsing polychondritis is described where primary involvement of the aortic valve cusps produced severe aortic regurgitation requiring valve replacement. An aneurysmal dilatation of the ascending aorta developing later led to disruption of the prosthesis requiring re-operation. Superior vena caval obstruction, an abdominal aortic aneurysm which ruptured and required resection, and obstructive lesions in common iliac arteries, presumably the result of the same process that involved the aorta and the cartilaginous structures, were also seen.

UI	MeSH Term	Description	Entries
D011081	Polychondritis, Relapsing	An acquired disease of unknown etiology, chronic course, and tendency to recur. It is characterized by inflammation and degeneration of cartilage and can result in deformities such as floppy ear and saddle nose. Loss of cartilage in the respiratory tract can lead to respiratory obstruction.	Polychondritis, Chronic Atrophic,Atrophic Polychondritides, Chronic,Atrophic Polychondritis, Chronic,Chronic Atrophic Polychondritides,Chronic Atrophic Polychondritis,Polychondritides, Chronic Atrophic,Polychondritides, Relapsing,Relapsing Polychondritides,Relapsing Polychondritis
D005260	Female		Females
D006350	Heart Valve Prosthesis	A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.	Prosthesis, Heart Valve,Cardiac Valve Prosthesis,Cardiac Valve Prostheses,Heart Valve Prostheses,Prostheses, Cardiac Valve,Prostheses, Heart Valve,Prosthesis, Cardiac Valve,Valve Prostheses, Cardiac,Valve Prostheses, Heart,Valve Prosthesis, Cardiac,Valve Prosthesis, Heart
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001012	Aorta, Abdominal	The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.	Abdominal Aorta,Abdominal Aortas,Aortas, Abdominal
D001019	Aortic Rupture	The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.	Aortic Aneurysm, Ruptured,Ruptured Aortic Aneurysm,Aneurysm, Ruptured Aortic,Aneurysms, Ruptured Aortic,Aortic Aneurysms, Ruptured,Aortic Ruptures,Rupture, Aortic,Ruptured Aortic Aneurysms,Ruptures, Aortic
D001021	Aortic Valve	The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.	Aortic Valves,Valve, Aortic,Valves, Aortic
D001022	Aortic Valve Insufficiency	Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).	Aortic Incompetence,Aortic Regurgitation,Aortic Valve Incompetence,Regurgitation, Aortic Valve,Incompetence, Aortic,Incompetence, Aortic Valve,Insufficiency, Aortic Valve,Regurgitation, Aortic