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Sigma SR and erythrocyte sedimentation rate (ESR) were compared before and after treatment with non-steroidal anti-inflammatory agents in 6 patients with rheumatic diseases. No evidence was found that either was altered by this kind of drug therapy, though there was considerable variation in the shape of sedimentation rate curves (obtained by plotting erythrocyte sedimentation rate every 5 minutes over 150 minutes), between individuals with the same disease.
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