Biomaterial Database

[Intracervical application of prostaglandin F2 alpha gel as low risk method of cervical dilatation for therapeutic abortion (author's transl)]. 1981

H Fritzsche, and H J Seewald, and R Voigt

In cases of interruption prostaglandin F2 alpha gel is applied intracervically and leads to dilatation of the cervix without any damage. This form of the therapy can be recommended because of its good results and harmless side effects.

UI	MeSH Term	Description	Entries
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011460	Prostaglandins F	(9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics.	PGF
D004107	Dilatation and Curettage	Dilatation of the cervix uteri followed by a scraping of the endometrium with a curette.	Curettage and Dilatation,Dilatation & Curettage
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000032	Abortion, Therapeutic	Abortion induced to save the life or health of a pregnant woman. (From Dorland, 28th ed)	Therapeutic Abortion,Abortions, Therapeutic,Therapeutic Abortions
D000287	Administration, Topical	The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.	Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations