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We have compared intercellular communication in normal and regenerating rat liver. Gap junctions are greatly reduced in size and numbers 29 to 35 hr after hepatectomy, but we still find some 90% of hepatocytes coupled by electrophysiological criteria. The spread of dyes such as carboxyfluorescein however is very limited in the regenerating organs as compared to the situation in the controls. We show how the apparent discrepancies between morphological and physiological data can be reconciled. We also present a summary of preliminary findings on the biosynthesis of gap junction protein and some of the conclusions one can draw from the sequence of 58 amino acids at the amino terminal of the protein.
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 1983,
Revisiones sobre biologia celular : RBC,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
September 1978,
Neurosciences Research Program bulletin,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 1997,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 2005,
Morfologiia (Saint Petersburg, Russia),
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
March 1971,
The Journal of membrane biology,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
November 1974,
Investigative ophthalmology,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 1982,
Harvey lectures,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
March 1992,
Science (New York, N.Y.),
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 1985,
Essays in biochemistry,
J P Revel, and
S B Yancey, and
D J Meyer, and
B Nicholson
January 1980,
Society of General Physiologists series,
