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The IOP reduction and regulation system performs certain specific functions: it can be used to lower (or raise) IOP in a controlled way; it responds rapidly to maintain a selectable, set, minimum IOP under variable flow demands; and it reduces the rapid dynamic increases in IOP resulting from loads applied to the eye. The system has been tested and evaluated in the laboratory with a small test chamber and excised animal eyes and subsequently with anesthetized live animals. The system has also had limited clinical use in selected patients. An expanded program of laboratory and clinical investigations is planned.
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