Acute effects of cigarette smoking on left ventricular function at rest and exercise. 1981

M J Behr, and K H Leong, and R H Jones

In this study we investigated the acute effects of cigarette smoking on cardiac function during exercise in 12 normal young males. Radionuclide angiocardiography was used to assess cardiac performance at rest and during upright-bicycle exercise on two consecutive days. On the second day each subject smoked three cigarettes. Exercise studies were continued until 85% of age-predicted heart rate for an individual was achieved. At rest cigarette smoking induced significant increases in resting heart rate, blood pressure, and contractility and significant decreases in end-systolic volume and pulmonary transit time. Comparison of hemodynamic data during exercise before and after smoking showed the only significant change to be a decrease in pulmonary transit time. These results suggest that cigarette smoking in healthy young males does not significantly alter cardiac function during submaximal exercise.

UI MeSH Term Description Entries
D008297 Male Males
D012146 Rest Freedom from activity. Rests
D002302 Cardiac Output The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat). Cardiac Outputs,Output, Cardiac,Outputs, Cardiac
D005082 Physical Exertion Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included. Physical Effort,Effort, Physical,Efforts, Physical,Exertion, Physical,Exertions, Physical,Physical Efforts,Physical Exertions
D006352 Heart Ventricles The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation. Cardiac Ventricle,Cardiac Ventricles,Heart Ventricle,Left Ventricle,Right Ventricle,Left Ventricles,Right Ventricles,Ventricle, Cardiac,Ventricle, Heart,Ventricle, Left,Ventricle, Right,Ventricles, Cardiac,Ventricles, Heart,Ventricles, Left,Ventricles, Right
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000790 Angiocardiography Radiography of the heart and great vessels after injection of a contrast medium. Angiocardiographies
D012907 Smoking Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand. Smoking Behaviors,Smoking Habit,Behavior, Smoking,Behaviors, Smoking,Habit, Smoking,Habits, Smoking,Smoking Behavior,Smoking Habits

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