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Pronounced differences in the phospholipase A2 activities were found in neurons and glia, the enzyme activity being two- to threefold higher in neurons than in glial cells. Both phospholipases A2 hydrolyzed the 1,2-diacylglycerophosphatides more rapidly than the acylalkyl and acylalkenyl compounds. Choline plasmalogen and the corresponding alkyl derivative were cleaved at similar rates by the phospholipase A2 from both glia and neurons. There was a tendency by the neuronal phospholipase A2 to release arachidonic acid faster than linolenic acid from both phosphatidylcholine and -ethanolamine, while arachidonic acid was removed less actively from phosphatidylethanolamine by the glial enzyme. The glial phospholipase A2 showed a lag period of 10 or 20 min. Norepinephrine, injection into the lateral ventricle of the rabbit brain, stimulated the hydrolysis of the various 1,2-diacyl-, acylalkyl, and and acylalkenyl-glycerophosphatides by the phospholipase A2 from both glia and neurons.
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
January 1974,
Journal of neurology,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
January 1974,
Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
February 1976,
Journal of neurochemistry,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
August 1974,
Biochemical and biophysical research communications,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
October 1974,
Journal of neurochemistry,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
September 1974,
FEBS letters,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
January 1976,
Advances in experimental medicine and biology,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
January 1977,
Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
March 1969,
Journal of lipid research,
H Woelk, and
G Arienti, and
A Gaiti, and
K Kanig, and
G Porcellati
November 1998,
Biochimica et biophysica acta,
