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A 36-year-old woman developed severe arterial hypertension after taking for five consecutive years increasing dose (up to 10 mg per day) of phenoxazoline HCl in nasal spray. A relationship between the abuse of this sympathomimetic drug and the hypertension was suggested by the unusual appearance of renal arteries on arteriography (stenosis and dilatations resembling aneurisms), the increase in renin activity and the disappearance of hypertension after the drug was discontinued. On control examination, two years later, blood pressure, renin activity and renal arteries were normal. The possibility of sympathomimetic drug overdosage must be borne in mind in cases of suspected iatrogenic arterial hypertension.
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
February 1978,
Kokyu to junkan. Respiration & circulation,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
September 1978,
Klinische Monatsblatter fur Augenheilkunde,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
January 1981,
Acta gastro-enterologica Belgica,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
January 1978,
Annales d'endocrinologie,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
November 1974,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
March 1979,
Klinische Monatsblatter fur Augenheilkunde,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
October 1979,
Haematologica,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
May 1981,
Der Urologe. Ausg. A,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
November 1974,
Revista medica de Chile,
J P Fendler, and
D Hillion, and
M Blain, and
A Bijard, and
G Dongradi
January 1980,
La Nouvelle presse medicale,
