Biomaterial Database

Lasalocid for improved weight gains and control of Coccidia in lambs. 1981

W J Foreyt, and S M Parish, and K M Foreyt

Lasalocid at 25 mg/kg of feed was highly effective in reducing numbers of oocysts in feces of naturally infected ewes and lambs. Treated ewes were fed lasalocid-medicated feed before and after parturition, and the 17 lambs from these ewes also were fed medicated feed gained 5.26 kg more (P less than 0.05) than did the 17 nontreated lambs from nontreated ewes. Naturally infected lambs maintained in semiconfinement acquired coccidia infections between 23 and 64 (mean of 38) days after birth. A coccidiostat given before and during the time coccidia-naive lambs were first exposed to coccidia was necessary to achieve the greatest production response to treatment. When naturally infected feeder lambs (30.9 kg) maintained in semiconfinement were fed lasalocid-medicated feed at 25 mg/kg of feed or unmedicated feed for 91 days, no significant difference (P greater than 0.05) in rate or efficiency of gain was detected, even though lasalocid was highly effective against coccidia.

UI	MeSH Term	Description	Entries
D007832	Lasalocid	Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It is used as a coccidiostat, especially in poultry.	Avatec,Lasalocid A,Ro 2-2985,X-537A,Ro 2 2985,Ro 22985,X 537A,X537A
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D003048	Coccidiosis	Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA.	Besnoitiasis,Besnoitiosis,Besnoitiases,Besnoitioses,Coccidioses
D005260	Female		Females
D000284	Administration, Oral	The giving of drugs, chemicals, or other substances by mouth.	Drug Administration, Oral,Administration, Oral Drug,Oral Administration,Oral Drug Administration,Administrations, Oral,Administrations, Oral Drug,Drug Administrations, Oral,Oral Administrations,Oral Drug Administrations
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000821	Animal Feed	Foodstuff used especially for domestic and laboratory animals, or livestock.	Fodder,Animal Feeds,Feed, Animal,Feeds, Animal,Fodders
D012756	Sheep	Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.	Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D012757	Sheep Diseases	Diseases of domestic and mountain sheep of the genus Ovis.	Ovine Diseases,Disease, Ovine,Disease, Sheep,Diseases, Ovine,Diseases, Sheep,Ovine Disease,Sheep Disease