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Flurbiprofen is a nonsteroidal anti-inflammatory (NSAI) agent currently undergoing clinical investigation. Anti-inflammatory steroids have long been known to delay the healing of corneal stromal wounds. This was designed to compare the effects of equipotent anti-inflammatory doses of flurbiprofen and of prednisolone acetate on the inflammation and the healing (as measured by the wound bursting pressure) or 4-mm through-and-through incisions treated four times a day for ten postoperative days. The results suggest that flurbiprofen and prednisolone are not different in their effect on both postoperative inflammation and postoperative wound healing. Since NSAI agents and steroids inhibit prostaglandin formation at different enzymatic steps, it is possible that prostaglandins not only are responsible for postoperative inflammation but also are required for postoperative wound healing.
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
January 1994,
Journal of refractive and corneal surgery,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
April 1983,
Archives of ophthalmology (Chicago, Ill. : 1960),
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
January 1997,
Documenta ophthalmologica. Advances in ophthalmology,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
October 2016,
International ophthalmology,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
June 2000,
Journal of cataract and refractive surgery,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
May 1994,
The British journal of ophthalmology,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
July 2013,
BMC ophthalmology,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
January 1995,
Nippon Ganka Gakkai zasshi,
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
April 1990,
Archives of ophthalmology (Chicago, Ill. : 1960),
D Miller, and
P Gruenberg, and
R Miller, and
M V Bergamini
November 1992,
Cornea,
