Biomaterial Database

ATP requirement for in vitro DNA synthesis in permeable cells of Bacillus brevis. 1981

S Bhattacharya, and N Sarkar

DNA synthesis in permeable cells of Bacillus brevis is almost completely dependent on the presence of ATP. Nevertheless, DNA synthesis in this system reflects primarily DNA repair rather than replication, as shown by the response to replication inhibitors, density shift experiments, and product size analysis. The apparent dependence of DNA synthesis on ATP was due to the stabilization of the deoxyribonucleoside triphosphate pools against degradation. These observations indicate that dependence of DNA synthesis on ATP is not a sufficient criterion for semiconservative DNA replication.

UI	MeSH Term	Description	Entries
D007700	Kinetics	The rate dynamics in chemical or physical systems.
D004261	DNA Replication	The process by which a DNA molecule is duplicated.	Autonomous Replication,Replication, Autonomous,Autonomous Replications,DNA Replications,Replication, DNA,Replications, Autonomous,Replications, DNA
D004269	DNA, Bacterial	Deoxyribonucleic acid that makes up the genetic material of bacteria.	Bacterial DNA
D000255	Adenosine Triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.	ATP,Adenosine Triphosphate, Calcium Salt,Adenosine Triphosphate, Chromium Salt,Adenosine Triphosphate, Magnesium Salt,Adenosine Triphosphate, Manganese Salt,Adenylpyrophosphate,CaATP,CrATP,Manganese Adenosine Triphosphate,MgATP,MnATP,ATP-MgCl2,Adenosine Triphosphate, Chromium Ammonium Salt,Adenosine Triphosphate, Magnesium Chloride,Atriphos,Chromium Adenosine Triphosphate,Cr(H2O)4 ATP,Magnesium Adenosine Triphosphate,Striadyne,ATP MgCl2
D001407	Bacillus	A genus of BACILLACEAE that are spore-forming, rod-shaped cells. Most species are saprophytic soil forms with only a few species being pathogenic.	Bacillus bacterium