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The effects of a single night of sleep deprivation on the amplitude and amplitude/stimulus intensity function of the visual evoked potential (EP) were studied in 16 patients with primary affective disorder and 20 normal controls. Visual EP amplitude and amplitude/intensity slopes tended to increase after sleep deprivation in the patient group, a direction found in other studies to be associated with a spontaneous mood improvement and changes with antidepressant medication. In contrast, normal volunteers who showed little or no mood elevation showed generally opposite EP effects. Taken together, the results suggest a similarity in the neurophysiological effect of sleep deprivation between patient and antidepressant medication in depressed patients.
M S Buchsbaum, and
R Gerner, and
R M Post
January 1979,
Journal of psychiatric research,
M S Buchsbaum, and
R Gerner, and
R M Post
May 1977,
Life sciences,
M S Buchsbaum, and
R Gerner, and
R M Post
July 1988,
Psychiatry research,
M S Buchsbaum, and
R Gerner, and
R M Post
August 1992,
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
M S Buchsbaum, and
R Gerner, and
R M Post
June 1987,
Psychiatry research,
M S Buchsbaum, and
R Gerner, and
R M Post
February 1976,
Acta psychiatrica Scandinavica,
M S Buchsbaum, and
R Gerner, and
R M Post
December 1981,
Psychiatry research,
M S Buchsbaum, and
R Gerner, and
R M Post
May 1976,
Archives of general psychiatry,
M S Buchsbaum, and
R Gerner, and
R M Post
March 1991,
Biological psychiatry,
M S Buchsbaum, and
R Gerner, and
R M Post
November 1975,
Psychophysiology,
