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The effect of coffee on lower oesophageal sphincter pressure (LOSP) and intraoesophageal pH was assessed in 10 healthy volunteers, in the fasting state and after a standard Lundh test meal. LOSP was measured by the rapid pull-through technique. Coffee with or without milk has no significant effect on LOSP in the fasting subject. The Lundh meal alone (mean drop = 2.01 cm H2O), or when coffee with (mean drop = 1.80 cm H2O) or without milk (mean drop = 3.47 cm H2O) was taken after it, produced a significant drop in LOSP. Heartburn following coffee does not appear to be due to an effect of coffee on the lower oesophageal sphincter but is more likely due to the effect of a previous meal on sphincter pressure with associated acid reflux.
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
April 1997,
Gut,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
December 1987,
Alimentary pharmacology & therapeutics,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
February 1977,
Gut,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
November 1998,
Clinical physiology (Oxford, England),
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
December 1999,
Neurogastroenterology and motility,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
August 2001,
Neurogastroenterology and motility,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
September 1976,
British medical journal,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
June 1994,
The British journal of surgery,
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
October 1969,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
P R Salmon, and
S S Fedail, and
H P Wurzner, and
R F Harvey, and
A E Read
January 1981,
Scandinavian journal of gastroenterology,
